Name | Quinazoline |
Synonyms | NSC 72372 Phenmiazine Quinazoline Benzopyrimidine 1,3-Benzodiazine Benzo[d]pyrimidine Benzo(a)pyrimidine Benzo(e)pyrimidine 4.5-Benzopyrimidine 5,6-Benzopyrimidine 1,3-Diazanaphthalene 1,3-Benzodiazine, Benzopyrimidine |
CAS | 253-82-7 |
EINECS | 205-965-3 |
InChI | InChI=1/C8H6N2/c1-2-4-8-7(3-1)5-9-6-10-8/h1-6H |
Molecular Formula | C8H6N2 |
Molar Mass | 130.15 |
Density | 1.2002 (rough estimate) |
Melting Point | 46-48 °C (lit.) |
Boling Point | 243 °C (lit.) |
Flash Point | 224°F |
Solubility | Soluble in water. |
Vapor Presure | 0.0545mmHg at 25°C |
Appearance | Crystalline Powder, Crystals and/or Chunks |
Color | Yellow to beige to brownish |
Merck | 14,8053 |
BRN | 109370 |
pKa | 3.43(at 20℃) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.6231 (estimate) |
MDL | MFCD00006712 |
Use | Usually used to study the electrochemical behaviour of quinazoline using modern polarographic and voltammetric methods. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S23 - Do not breathe vapour. |
WGK Germany | 3 |
HS Code | 29339900 |
Reference Show more | 1. [IF=3.943] Liwei He et al."4(3H)-Quinazolone regulates innate immune signaling upon respiratory syncytial virus infection by moderately inhibiting the RIG-1 pathway in RAW264.7 cell."Int Immunopharmacol. 2017 Nov;52:245 |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
production method | is prepared by reducing o-nitrobenzyldicarboxamide with zinc powder and dilute acetic acid. |